The term ‘medically unexplained symptoms’ although historically widely-used has recently been replaced by labels which are less stigmatising to the patient and, at the same time, acknowledge the uncertainty that continues to inform somatoform syndromes. In this study, the term ‘Persistent Physical Symptoms’ (PPS) is used to describe these conditions.

It is estimated that between one third and one half of all patients referred to out-patient clinics present with impaired functioning which either lacks or is insufficiently explained by structural or neurological pathology. Consultants frequently describe this population as disproportionately time-consuming and difficult to treat. Service users report that their symptoms and concerns are frequently dismissed during consultations.

Sitting at the intersections between mind, body and brain, somatic pathology challenges both the current structure of specialised medical disciplines within the general hospital, and the lack of integration between psychiatric and medical services. In addition to the distress and disability experienced by somatising patients, the cost to the annual UK economy is approximately £18 billion.

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Understanding of somatoform disorders focuses on the relationships between predisposing, precipitating and perpetuating factors.

A. Predisposing

1) Genetic: the expression of an inheritable predisposition to general distress (stress-diathesis)
2) Early childhood environment:

I) vicariously learned illness behaviour
II) illness scripts: learning that physical illness was rewarded with care-givers’ attention
III) over-protective parents/care givers
IV) physical, emotional and/or sexual abuse, or developmental trauma
V) adoption

3) Neuroticism: a personality trait referring to a stable, life-long tendency to experience negative affect and somato-psychic distress (Watson & Pennebaker, 1989).

B. Precipitating

1) Genetic: the expression of an inheritable predisposition to general distress (stress-diathesis)
2) Traumatic event, e.g. bereavement

C. Perpetuating

1) Sensitisation: heightened response to stimuli as a result of prior experience; memory traces may be at a neuronal or sensory level and are underpinned by the patient’s psychological formation, setting in motion an autopoietic process (Kano & Fukudo, 2013)
2) Endocrine dysregulation: acute or chronic stress may result in the down regulation of the Hypothalamus Pituitary Adrenal (HPA) axis and the increased experience of bodily symptoms
3) Attention: somato-sensory amplification, as a result of faulty filtering of bodily symptoms, leads to misinterpretations of physical signs and sensations (Ursin, 2005)
4) Attribution: illness beliefs and behaviours are shaped by high estimates of illness vulnerability (MacLeod, Haynes, & Sensky, 1998)$
5) Cognitive inflexibility: maladaptive cognitive styles including over-generalising, magnifiying, dichotomous thinking, fortune-telling, ‘jumping to conclusions’ and catastrophising, resulting in fixity and exclusivity of somatic explanations, and the production of dysfunctional coping mechanisms
6) Avoidance: resistance to experience discomfort and/or to exercise
7) Emotional avoidance: reluctance to experience and/or process emotions (Derakshan, Eysenck & Myers, 2007)
8) Graded Activity: patients who fail to follow a graded exercise schedule, and experience cycles of ‘boom or bust’
9) Intentionality: mismatch between actual and predicted sensory feedback (as evidenced in hypoactivation of temporoparietal junction on fMRI (Edwards & Bhatia, 2012)
10) Secondary gains: conscious/unconscious elicitation of caring behavior
11) Physical co-morbidity: existence of organic disease that is unrelated to somatic presentation
12) Personality disorders (PD): predominantly borderline and narcissistic PD
13) Psychiatric co-morbidities: predominantly high levels of anxiety and moderate to severe depression.



Most of the patients who attend the Persistent Physical Symptoms Group struggle to articulate their feelings. Most have impaired mentalization skills; some also are alexithymic. Many experience anger with inter alia their families, friends, physicians – and their symptoms, although many are unable to express this emotion.

The two models of anger (Volcano and Iceberg) are graphic depictions of the autonomic arousal system. Patients report that the diagrams help them understand how they typically cope with distress. Individuals may demonstrate hyper – or hypo – arousal, although some may ‘yo-yo’ between the two arousal states. A main objective of the Group protocol is to expand participants’ ‘Window of Tolerance’ (Fisher, 2008) and enable them to tolerate simultaneously feelings and reactions. Learning to react appropriately to situations - and practising new behaviours in the safe space of the Group – enables participants to give up previous self-sabotaging behaviours. In this way, emotional regulation and assertiveness skills are expanded.

Mindfulness exercises are practised on a regular basis, using all 5 senses. The scent of a rose and the colour and texture of its petals helps ground patients in the present moment, as does the crunch and taste of popcorn or the juice of ripe berries as it squirts out of the fruit. For some patients, focused attention is better achieved through the sound of rain or waves crashing on rocks. These exercises undermine patients’ tendency to ruminate and help them focus attention, thereby weakening their often disproportionate focus on their symptoms. (Mindfulness breathing is not included as there is evidence that anxious individuals may struggle to focus and become even more anxious).

Extreme health anxiety is not uncommon amongst sufferers of conversion disorders, and somatisation and other related disorders (DSM-5 (2013), 300.7, 330.82, 300.89, 300.11; ICD-10 (1992), F44.4-44.9, F.45.1-45.9). Dismantling idiosyncratic and dysfunctional illness beliefs and narratives helps undermine some  of their rigid fears. Enhancing emotional and psychological flexibility is a key objective of the Group protocol.

Weekly homework is given in order to reinforce the work of the group, allow participants to reinforce their progress and to help measure their motivation to recover. An important between-session task, for example, are the somatic & behavioural experiments that reflect the values identified by group members as important to their life. Potential obstacles to the success of the experiment are identified at the design stage and strategies devised to overcome them. Perfectionist tendencies – as frequently seen in ‘boom or bust’ activities’ are similarly pre-empted at an early stage. Review of the experiment allows patients to acknowledge success, thus boosting their sense of self-efficacy and self-esteem. Partial success demands that patients learn to adapt and develop flexible expectations. Dealing with disappointment leads to group work on self-compassion.

Relapse prevention and resilience skills inform the later stages of the group. The Resilience Box serves both as a ‘transitional object’, a connection to the group, as well as a rapidly accessible resource in challenging times.

Note on materials: all materials used have been developed or modified for use with somatic conditions. As this patient population tends to tire easily and may have impaired concentration and memory, materials rehearse the teaching of the session as well as introduce new tasks. The materials have been designed so that they can also be used with patients with mild learning difficulties.

The 3 and 6 month follow-up offers an opportunity for patients to reflect on how they have managed without the weekly support, and to identify any new challenges.

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Male and female patients between the ages of 18 and 65 with chronic functional symptoms, often (but not always) involving multiple body systems, were referred by the acute general hospital. Following an extensive biopsychosocial assessment, those who met the criteria for inclusion were invited to attend the group intervention. Each group had a maximum of eight participants.

The individuals in each group presented with a range of conditions, reflecting the ‘lumping’ rather than ‘splitting’ philosophy of the intervention

Patients’ conditions included conversion disorders, non-epileptic attack disorder, movement disorders, gastro-intestinal, respiratory disorders and somatoform (pain) disorders.

Patients who were floridly psychotic and those who did not possess adequate English language skills were excluded from the group.

All the measures used were based on self-report.

Pre-Group Measures

  • Warwick-Edinburgh Mental Well-being Scale (WEMWBS, Stewart-Brown et al, 2008), is a 14 item self-report Likert scale of mental well-being covers subjective well-being and psychological functioning. Items address aspects of positive mental health.
  • EuroQual - 5Dimensions (EQ-5D, Lamer et al, 2005), is a generic self-report instrument for measuring health-related quality of life measures that can be translated into costs to the health and wider economy. Five domains are evaluated: mobility, self-care, pain/discomfort, anxiety/depression, and ability to perform usual activities. A visual analogue scale (EQ-VAS) provides a snapshot of the patient’s health status.
  • Scale for Evaluating Physical Symptoms (SEPS, Tyrer et al, 2012). Patients report their main physical symptoms, their persistence, severity, and chronicity. A Likert- type scale measures the severity of their most disabling symptom, its impact on their ability to exercise, and evaluates whether they consider that they need further investigation.
  • This measure is currently being adapted to include patients with functional neurological conditions as well as those who present with co-morbid disabling psychiatric illnesses.
  • Mood and Motivation Measure (MMM, Scheiner, 2012, unvalidated) is a quantitative and qualitative measure of the patient’s perception of their engagement and belief in the recovery process. Twenty-five items are framed in a mixture of both positive and negative terms. Answers are scored on a Likert scale. The Measure also includes two questions that ask the patient to reflect on what else they need to do to enhance their progress.
  • Toronto Alexithymia Scale (TAS-20, Bagby et al, 1994) is a 20 item measure of the individual’s ability to identify and measure emotions. Respondents’ answers are scored on a Likert scale.
  • Health Anxiety Inventory (HAI, Salkovskis, 2002) is used with patients who present with hypochondriasis. Fourteen items evaluate current symptoms and the patient’s ability to be reassured by results that do not detect abnormal pathology. Four subsequent items ask the patient to imagine the impact on their quality of life of being diagnosed with a life-limiting illness.
  • Karnofsky Scale is a clinician-administered performance rated scale of the patient’s current presentation. This measure is currently being adapted to capture a more nuanced record of the patient’s functioning, for example, their mentalization skills.

Participants also completed a demographic form documenting their health care over the previous year, including GP and outpatient consultations, procedures and investigations and hospital admissions. The form included space for them to describe both their illness beliefs and recent stressors. Possible stressors included childhood or adult trauma, parental physical and mental health status and financial worries.

Weekly Measures

  • WEMWBS; EQ-5D.

End of group measures and follow-up (3 and 6 months):

At the end of the 12 sessions, patients complete a Feedback form which includes an evaluation of the progress they have made and asks them to identify SMARTIE goals for the next three and six months.

  • EQ-5D
  • SEPS
  • MMM


The findings to date indicate that patients improve their quality of life and reduce their number of unplanned GP and consultant appointments independent of improvements in their physical symptoms.

Quantitative and qualitative data indicated greater emotional awareness and improved quality of life, independent of physical symptoms. Health care utilisation decreased. These benefits were maintained at three month follow-up.

The EQ-5D descriptive system and the EQ VAS descriptive system comprises the following 5 dimensions: mobility, self-care, usual activities, pain/discomfort and anxiety/depression. The Graph shows that over the life time of the Group, each dimension decreased in levels of severity, which means that patient’s quality of life improved as the weeks continued.

(It should be noted that the numerals 1-5 have no arithmetic properties and should not be used as a cardinal score.)

(It should be noted that the numerals 1-5 have no arithmetic properties and should not be used as a cardinal score.)

The WEMWBS is a a measure of 14 positively worded items with five response categories, for assessing patient’s mental wellbeing. The WEMWBS graph shows that patients scores increased from 37.5 to 40.00, demonstrating a meaningful improvement in patients' wellbeing over the course of the 12 week sessions project.

Future Developments

It is planned to add both weekly physiotherapy and occupational therapy. The aims are to improve patients’ mobility and reduce pain and discomfort, whilst at the same time, increasing their repertoire of activities and the pleasure they derive from performing them.


  • The group provides a secure base in which to explore emotional, social and physical challenges
  • Group interaction promotes both psychological understanding and affect regulation.
  • Enhanced cognitive flexibility promotes adaptive illness behaviours. The protocol is a low-cost intervention per quality-adjusted life-year (QALY).
  • Patients with co-morbid narcissistic personality disorder require individual treatment before joining the group.
  • Motivation to change fluctuates in this patient population.

Declaration of interests

  • No financial sponsorship was received for the Pilot



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